Christian Giaume Selected Research

boldine

1/2020	Connexin 43 deletion in astrocytes promotes CNS remyelination by modulating local inflammation.
10/2017	Inhibition of glial hemichannels by boldine treatment reduces neuronal suffering in a murine model of Alzheimer's disease.

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Christian Giaume Research Topics

Disease

6	Alzheimer Disease (Alzheimer's Disease) 01/2019 - 03/2006
3	Inflammation (Inflammations) 01/2020 - 09/2010
2	Epilepsy (Aura) 01/2018 - 08/2009
2	Narcolepsy 01/2018 - 01/2016
2	Neurodegenerative Diseases (Neurodegenerative Disease) 10/2017 - 02/2009
2	Neuroinflammatory Diseases 01/2017 - 05/2015
2	Gliosis 01/2017 - 01/2017
2	Hypoxia (Hypoxemia) 09/2011 - 02/2010
2	Ischemia 02/2010 - 02/2009
1	Brain Diseases (Brain Disorder) 01/2021
1	Demyelinating Diseases (Demyelinating Disease) 01/2020
1	Cardiovascular Diseases (Cardiovascular Disease) 01/2019
1	Hypertrophy 01/2019
1	Pathologic Processes 01/2019
1	Neoplasms (Cancer) 01/2019
1	Glioblastoma (Glioblastoma Multiforme) 01/2019
1	Cataplexy 01/2018
1	Disorders of Excessive Somnolence (Hypersomnia) 01/2018
1	Seizures (Absence Seizure) 01/2018
1	Amyloid Plaque 01/2017
1	Hyperalgesia 12/2016
1	Neuralgia (Stump Neuralgia) 12/2016
1	Sleep Wake Disorders 01/2016
1	Sleepiness 01/2016
1	Edema (Dropsy) 08/2012
1	Stroke (Strokes) 02/2010
1	Communicable Diseases (Infectious Diseases) 02/2009
1	Retinoblastoma (Glioblastoma, Retinal) 01/2009
1	Encephalitis (Encephalitis, Rasmussen) 12/2007
1	Glioma (Gliomas) 11/2006

Drug/Important Bio-Agent (IBA)

9	Connexin 43 (Connexin43)IBA 01/2020 - 01/2009
4	Proteins (Proteins, Gene)FDA Link 01/2019 - 02/2009
4	ConnexinsIBA 01/2019 - 08/2012
4	Glucose (Dextrose)FDA LinkGeneric 09/2011 - 11/2006
3	Peptides (Polypeptides)IBA 01/2018 - 02/2010
2	boldineIBA 01/2020 - 10/2017
2	Modafinil (Provigil)FDA Link 01/2018 - 01/2016
2	Amyloid beta-PeptidesIBA 01/2017 - 03/2006
2	Glial Fibrillary Acidic ProteinIBA 01/2017 - 08/2012
2	Adenosine Triphosphate (ATP)IBA 10/2013 - 02/2009
1	Complement System Proteins (Complement)IBA 01/2021
1	Lysophosphatidylcholines (Lysophosphatidylcholine)IBA 01/2020
1	AlkaloidsIBA 01/2020
1	1- Methyl- 4- phenyl- 1,2,3,6- tetrahydropyridine (MPTP)IBA 01/2019
1	Ion Channels (Ion Channel)IBA 01/2019
1	Intercellular Adhesion Molecule-1 (Intercellular Adhesion Molecule 1)IBA 01/2019
1	Fluorescent Dyes (Fluorescent Probes)IBA 01/2019
1	TAT-Gap19 peptideIBA 01/2018
1	Anticonvulsants (Antiepileptic Drugs)IBA 01/2018
1	Pilocarpine (Ocusert)FDA LinkGeneric 01/2018
1	Serine (L-Serine)FDA Link 01/2018
1	Neuroprotective AgentsIBA 10/2017
1	Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA 01/2017
1	Amitriptyline (Elavil)FDA LinkGeneric 12/2016
1	Mefloquine (Lariam)FDA LinkGeneric 12/2016
1	Tricyclic Antidepressive Agents (Tricyclic Antidepressants)IBA 12/2016
1	Antidepressive Agents (Antidepressants)IBA 12/2016
1	Flecainide (Tambocor)FDA LinkGeneric 01/2016
1	EndotoxinsIBA 05/2015
1	Dystroglycans (Dystroglycan)IBA 08/2012
1	Aquaporins (Water Channels)IBA 08/2012
1	Amyloid (Amyloid Fibrils)IBA 09/2011
1	p38 Mitogen-Activated Protein KinasesIBA 02/2010
1	Coloring Agents (Dyes)IBA 02/2010
1	CyclinsIBA 01/2009

Therapy/Procedure

3	Therapeutics 01/2018 - 01/2016
1	Injections 01/2017